Antidepressants Increase Bdnf Synthesis And Signaling In The Hippocampus And Prefrontal Cortex.
While reading about fasting and the benefits of autophagy I came across this article by Mark Sission:
"Fasting Increases Levels of Brain-Derived Neurotrophic Factor (BDNF)
BDNF is a protein that interacts with neurons in the hippocampus, cortex, and basal forebrain (the parts of the brain that regulate memory, learning, and higher cognitive function â€“ uniquely human stuff). It helps existing neurons survive while spurring the growth of new neurons (neurogenesis) and the development of synapses (lines of communication between neurons). Low levels of BDNF are linked to Alzheimerâ€™s, and supplementary BDNF prevents neuronal death, memory loss, and cognitive impairment in an animal model of Alzheimerâ€™s disease."
"Essentially all antidepressant treatments increase BDNF synthesis and signaling in the hippocampus and prefrontal cortex."