Wood Frogs Can Freeze Solid For Several Months, Thaw, And Return To Life

Viable in humans? :wink:

"The researchers also discovered that the frogs don't freeze once and stay frozen. Instead they spend a week or two freezing at night and thawing during the day, until the temperature drops permanently below freezing.

Larson thinks this thawing and freezing patterns helps the frogs convert more of the glycogen stored in their liver into glucose. This is essential because it is the high levels of glucose in the frogs' cells that keep them alive throughout the long, cold winter.

The glucose's main function is to keep water inside the cells. Frostbite in humans is caused when the water in our blood outside turns to ice. That hyperconcentrates the fluid around the cells and tissues, which in turn draws water out of the cells. Eventually the cells get so dehydrated that they die.

Larson offers this analogy: "If you put a potato in salty water, the whole potato kind of shrivels up because all the water from the potato goes to the higher concentration of salinity, but if you add a bunch of salt to a potato, it would retain its water," he said.

By making the cells super sweet with glucose, the frogs keep the water from leaving their cells."



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