Dopamine-Effect From Methylfolate/hydroxocobalamin Possibly Disappearing When Combined With Coffee
I have realized that I have a huge dopamine-deficiency (add-symptoms). Last Thursday I came across this: http://www.longecity.org/forum/topic/64835-chronic-dopamine-deficiency-consistently-disappearing-during-alcohol-hangovers/
Me and the "Thread starter" (not completely sure what the proper English-term is) seemed to correlate very much in our experiences with hangover, ciltep and the combo methylcarbonate and methylfolate. Both with ciltep and the methylcarbonate/methylfolate-combination we felt great the first days/weeks but pretty quick the effects faded. I therefore decided to try his recomendations which were:
Â· 200 mcg of oral methylfolate, every six hours (6 hours is about how long the effect lasts)
Â· 1 mg of hydroxocobalamin once a day
He seemed to have got extremely good results from this combination and there is no buildup in tolerance. The only downside seemed to be a somewhat high level of hemoglobin in the blood (he has been using the combination for over a year) but nothing more.
Yesterday my package arrived. Since I got home somewhat in the evening I just took 800 mcg methylfolate (orally) and 1 mg of hydroxocobalamin (sublinugally). That made me feel great. Today I took 1 mg of hydroxocobalamin and 400 mcg methylfolate in the morning with my BP-coffee with no effect. A couple of hours later I tried 1 mg of hydroxocobalamin and 400 mcg methylfolate again and this time I felt a great effect again. I realized that there was a possibility that the coffee had something to do with it and after some google-searching I found a couple of sources that strengthened my belief. Since this only has happened one time it doesnâ€™t have to be the coffee that is the problem, but the effect when talking with/without coffee was really noticeable. I now have a couple of question:
- Do you think that BP-coffee (and any other coffee for that matter) could lower the effect of my methylfolate/hydroxocobalamin-combination?
- If so, does anyone have an idea what to drink/eat for breakfast instead?
- Could this lowering of effect be prevented by a higher dose of methylfolate/hydroxocobalamin, and in that case could high doses of hydroxocobalamin and/or methylfolate be dangerous?