Liftmode - Phenibut Review

Jason HooperJason Hooper ✭✭✭
edited June 2013 in Sleep Hacking

I must begin this review by disclosing that I have entered into an agreement with Liftmode to review their Phenibut product in exchange for twenty American dollars in store credit.  They did not tell me that I had to write a favorable review, so I am free to write anything that I want.


 


Since my wife has entered her second trimester, her sleep quality has been suffering.  She tosses and turns throughout the night.  I do not consciously notice this, but my Zeo sure does!  Here is a typical night of data:


 


Before.JPG


 


I would wake up feeling exhausted.  My mood was wretched, my creativity suffered, and my joints began to ache.  I needed to hack my sleep, so I went back to a supplement that I vowed never to take again--GABA.  It helped my sleep, but the side effects were brutal.  Thirty minutes after taking it, I would get a metallic taste in my mouth, my respiration would increase, and I would just feel awful.  After doing some research, I found that GABA does not cross the blood-brain barrier very effectively.


 


320px-Gabapentin_3D.png


See how the amine (blue) and carboxyl (red) backbone is deformed?  The side chain is also misshaped.  In the 1960s, Soviet scientists addressed this issue by developing a drug called Noofen which changed the side chain to a phenyl ring to form Î²-phenyl-γ-aminobutyric acid.


 


Phenibut.gif


 


Here is a great document that talks about the pharmacology:


 


http://onlinelibrary.wiley.com/doi/10.1111/j.1527-3458.2001.tb00211.x/pdf


 


I began to look for a product to self experiment with.  The encapsulated versions were expensive, so I found it in the form of crystallized granuals from Liftmode.


 


http://www.amazon.com/gp/product/B0085Z31US/ref=oh_details_o05_s01_i01?ie=UTF8&psc=1


 


They test their each batch for impurities and have set the minimum requirement for 99.8 percent purity.  I found that to be impressive.


 


The bad:


 


To stabilize their product, Liftmode went with a hydrochloric compound.  If you are prone to acid reflux, this may be a problem for you.


There are still some side effects, but they are far less than taking GABA.


Although it has an effect on bega-GABA (rather than a-GABA) it is physically addictive.


This product can be hard on the liver if taken regularly at doses that exceed fifteen grams.


 


The good:


 


I will let the data speak for itself:


 


After.JPG


 


I woke up feeling amazing.  My joints feel good.  I took a shower than started composing some really great music.  I plan on using no more than a gram per night and cycling this product regularly.


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Comments

  • John BrissonJohn Brisson The Legend Formerly Known as Ron Swanson ✭✭✭
    edited June 2013

    Phenibut has issues with physical addiction in some people and has been linked to cause withdrawl symptoms. It should only be used sparingly my friend. With that note it definitely does work. http://www.socialanxietysupport.com/forum/f56/phenibut-84136/


    My book Fix Your Gut, is offered on Amazon for $9.99.

     

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  • katolotuskatolotus ✭✭✭

    Some info on GABA on the 'Not Just Paleo Podcast' with Beverly Meyer (23rd April 2013). Might be worth a listen if you're interested in this product.


    Katolotus

    MMA Fighter

     

    SUCCESS: A lot of little things done well

  • I have updated my post to include that information.  I will look for a way to hack the adrenergic storm by cycling tyramine suppressors.  What would you suggest?  Zinc?  Bystolic?  Grapefruit seed extract?  Oregano oil?


  • What are your thoughts on using L-Tryptophan before sleep?


  • John BrissonJohn Brisson The Legend Formerly Known as Ron Swanson ✭✭✭

    I have updated my post to include that information.  I will look for a way to hack the adrenergic storm by cycling tyramine suppressors.  What would you suggest?  Zinc?  Bystolic?  Grapefruit seed extract?  Oregano oil?


    Zinc, I would only go with zinc.

    My book Fix Your Gut, is offered on Amazon for $9.99.

     

    I also offer coaching:  http://fixyourgut.com/health-coaching-information/

     

    Please join or like the Fix your Gut Facebook. Also please add me on twitter @FixYourGutJB.

     

    http://www.fixyourgut.com

     

  • Evan BrandEvan Brand Writer and Explorer

    Some info on GABA on the 'Not Just Paleo Podcast' with Beverly Meyer (23rd April 2013). Might be worth a listen if you're interested in this product.


    Thanks Katolotus, I use a GABA supplement which Beverly didn't seem to prefer.


     


    She said that it's great if it works for you, but prefers to recommend passionflower for anxiety relief and pleasurable relaxation at lower doses, to knocking you on your ass at higher doses.


     


    Here's the link to the episode.

    Evan Brand, NTP, CPT

    Functional Medicine Practitioner and Podcast Host at NotJustPaleo.com

    Author of REM Rehab and Stress Solutions

  • Jason HooperJason Hooper ✭✭✭
    edited June 2013

    Thanks!  I will have to research chrysin flavones in more detail.  It is relatively toxic, but it does not have the benzo-like rebound.  


     


    Dr. Meyer sparked my interest with the idea of "leaky brain."  I will have to research proteins that cause problems in the blood-brain barrier.  Obviously gluten is one of them, but I suspect there are many others.


  • Really interesting post Jason! This is some ground-breaking stuff your posting on here..not heard of this Phenibut before

  • @Jason Hooper: what dosage of GABA were you taking to experience those side effects?


  • Anything over a gram will give me a reaction.


  • katolotuskatolotus ✭✭✭
    edited June 2013

    Just ordered some GABA to try out :wink:


    Katolotus

    MMA Fighter

     

    SUCCESS: A lot of little things done well

  • In Podcast 45, Dave Asprey recommends it quite strongly for both anxiolytic effects during the day, and to help cure jet lag (and presumably sleep at night).


     


    I've found 500mg to work pretty well to quieten the 'monkey brain' at night, but I haven't really paid attention to any side effects that might arise the next morning. Perhaps you'll be alright as long as you use less than 1000mg?


     


    In the podcast he mentioned that he's also experimenting with a more bioavailable form of GABA that might be released as a product soon.


  • Any update on this?


     


    I use:


     


    -300mg phenibut with ginger 15mg once a week 


    -10mg magnesium and valerian once week


    -ZMA 1 tab once a week


     


    I cycle off inbetween days for the rest of the week.


     


    Sleep great every night, but the best night is with the phenibut (subjective). Are you cycling on and off?


    Reigning Former Inner Balance "Mad Monk" Champion... :-P 

  • ArcArc
    edited June 2013

    I have been using phenibut for a few years now - I try to limit use to 1 - 2 times a week.


     


    Too much phenibut gives a hangover - which is very much like being drunk, but without the mental retardation.


     


    I have found it excellent at changing my sleep cycle, because if you take enough of it (3-4 grams); you will find it very easy to sleep.


     


    Also from my experience (Zeo) it doesn't reduce deep sleep, which I believe is an issue with GABA-A pharmaceuticals.


     


     


    I have used GABA in the past, and it definetely has strange side-effects; which aren't very comfortable, so I ended up throwing the rest of it out.


     


     


    In terms of an excellent sleep stack:


    • Melatonin
    • Taurine
    • Glycine
    • Theanine
    • Magnesium

    I have however run out of theanine, and magnesium.


     


    But the above works rather well, and you can add in phenibut or something less strong like valerian, chamomile, lemon grass or passion flower if the need arises. Note that some of the herbs have an in inhibitory effect on thyroid, so I would use very sparingly.


     


    Above all I think that sleep is a skill in some regards - if you are not suffering from external environmental factors (i.e. other people snoring etc) - and that the more you sleep better, the better you become at sleeping.


    So I haven't felt the need to replace the magnesium or theanine; and I could probably make do on the melatonin alone now.


  • this is my review of Liftmode Phenibut


    5 stars


     


     


    Been using bout 4 months.


    Keeping a steady supply even if overnighted.


    Best source is from Liftmode website itself.


     is great to take instead of  Pills. I do take 1000mgs twice a day, so its a little more than the recommended, but it works! No prob with success. Just remember to take a few days off, no Pheibut for 2 or 3 days, then go back on.


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