Huperzine A, Choline, Racetams, And The Brain
In the upgrading your brain post Dave talks about the benefits of Huperzine A, and I have read elsewhere too that it is supposedly good for memory and general cognition. However, Dave cautions that it may not be for everyone. Apparently you can be Choline dominant or not, and Huperzine A raises acetylcholine. This is helpful for some people but not others. Aniracetam and Piracetam lower Choline. I know Choline is something that we want (or at least is good for most people?) and it's good for brain health. Presumably we should consume more Choline if we're taking racetams? I usually get my Choline for egg yolks in my BPC but I know it can be supplemented. I don't really know much about acetylcholine or how it interacts with regular Choline levels.
Dave's comments are here:
Huperzine A is an alkaloid found in the plant moss Huperzia serrota. This plant has been used medicinally for headaches, swelling, fever, and blood disorders by the Chinese for centuries. It enhances memory, increases nerve growth, and protects against Alzheimerâ€™s. It also increases REM sleep. But beware; it raises acetylcholine levels, which is helpful in 2/3 of people, but harmful in those who are choline dominant (like me). Watch out for a clenching jaw or headaches â€“ if you get those, stop taking it, and double up on Aniracetam until the symptoms go away. (the racetams lower choline, which is a good thing if you have too much!)
Does anyone have any expertise or experience with combining these substances? Or can anyone better help me understand how these different compounds work for or against each other.